Tachyarrhythmia is an abnormal cardiac rhythm with a heart rate of 100 or more beats per minute. It may be asymptomatic or highly symptomatic and life-threatening. A 12-lead electrocardiogram forms the mainstay of diagnosis.
Presentation
Tachyarrhythmia is a type of abnormal cardiac rhythm and is classified based on its site of origin as ventricular (originating below the bundle of His) or supraventricular (above the bundle of His). Ventricular tachyarrhythmias include ventricular tachycardia (VT), ventricular fibrillation (VF), and premature ventricular contraction (PVC). Supraventricular tachycardia (SVT) or paroxysmal supraventricular tachycardia (PSVT) presents a rapid heart rate anywhere between 150-250 beats per minute and is further classified as atrioventricular nodal reentrant tachycardia (AVNRT), atrioventricular reciprocating tachycardia (AVRT), atrial tachycardia (AT), atrial fibrillation and atrial flutter. The clinical presentation of tachyarrhythmias may vary depending on the type of arrhythmia from asymptomatic to chronic and recurrent or highly symptomatic and life threatening. Common symptoms in all tachyarrhythmias include palpitations, chest discomfort, dyspnea, fatigue, lightheadedness, and dizziness. Uncommon symptoms comprise diaphoresis, nausea, presyncope, and syncope.
VT is a tachyarrhythmia of >100 beats per minute which is regular while VF is a more serious type of tachyarrhythmia with an asynchronous discharge of impulses causing the heart to beat erratically, often at a rate > 300 beats per minute. This results in poor perfusion of organs, especially the brain, with possible fatal outcomes. VF is commonly seen in individuals with cardiac disease or a recent history of myocardial infarction. PVCs are a less serious type of tachyarrhythmia with the ventricle contracting prematurely and out of sequence to the normal heart beat. They often start suddenly without a warning and can be stimulated by caffeine, chocolate, and some medicines.
The commonest type of SVT is AVNRT which affects young, healthy women [1], often without structural cardiac disease, though some patients may have pericarditis, previous myocardial infarction, or mitral valve prolapse [2]. AVRT is the second most common type of SVT and is caused by accessory tracts which conduct the abnormal impulses proximally as well as distally creating a reentry circuit [3]. AVRT can occasionally occur with Wolff-Parkinson-White syndrome and may spontaneously degenerate into atrial fibrillation [4]. AT is the third most common type of SVT arising from a focus in the atrium [5]. It is of two types: focal and multifocal AT (MAT). Focal AT originates from a definite focus like the crista terminalis in the right atrium or the ostia of the pulmonary veins in the left atrium [6] [7]. MAT is frequently seen in patients with congestive heart failure or chronic obstructive pulmonary disease [6]. SVT symptoms depend on the patient's age, comorbid medical conditions, and duration of the episodes.
Atrial fibrillation (AF) is a type of SVT and a common cause of stroke and congestive heart failure [8]. Atrial flutter is an irregular SVT originating in the atria which may be asymptomatic in the initial stages or may be associated with palpitations, later degenerating into AF. Wolff-Parkinson-White syndrome is characterized by abnormal accessory conduction pathways (bundle of Kent) between the atria and the ventricle.
Workup
Tachyarrhythmias can be detected by history and physical examination but the diagnosis is confirmed by a 12-lead electrocardiogram (ECG) or a rhythm strip. Often SVT episodes are misdiagnosed as anxiety or panic attacks especially in the presence of a psychiatric disorder [8]. A high index of suspicion is, therefore, important to make a diagnosis [9]. The initial evaluation should determine whether a patient is hemodynamically stable. A brief cardiovascular examination will determine the ventricular rate and its regularity while the nature of the jugular venous pulse waves may also help to detect tachyarrhythmias. In a stable, symptomatic patient, it is important to obtain a 12-lead ECG while a rhythm strip is an initial assessment measure in an unstable patient prior to emergency cardioversion.
The ECG findings are characteristic for each tachyarrhythmia. A supraventricular origin of the tachyarrhythmia is indicated by a narrow QRS complex (< 0.12 sec) while a wide QRS complex (≥ 0.12 sec) indicates a ventricular origin or an SVT conducted by an intraventricular conduction defect or preexcitation in the Wolff-Parkinson-White syndrome. AF features are irregular, continuous, rapid beats at a rate >300 beats/ minute without discrete P waves. If the P waves are discrete and vary with every beat with at least 3 different morphologies then it is suggestive of MAT. Atrial flutter appears as regular, discrete, uniform P waves without intervening isoelectric periods at rates > 250 beats/min while AT features include regular, discrete, uniform, abnormal P waves with intervening isoelectric periods at rates < 250 beats/min. In VF, the rhythm strip will show rapid, irregular heart rate up to 300 beats/ minute. If the QRS complex varies with every beat, then the tachyarrhythmia is called polymorphic VT and the most notorious form of polymorphic VT is torsades de pointes.
Laboratory tests should include serum electrolytes, calcium, phosphate, as well as cardiac troponin level assessment. Echocardiography helps to assess the status of the heart while Holter monitoring is indicated in patients with recurrent tachyarrhythmias. Other tests like stress test may be performed as indicated during the clinical evaluation of the patient.
Treatment
Treatment for tachyarrhythmia depends on the type and severity of the condition. Options may include lifestyle changes, medications to control heart rate or rhythm, and procedures such as electrical cardioversion or catheter ablation. In some cases, a pacemaker or implantable cardioverter-defibrillator (ICD) may be recommended to help regulate the heart's rhythm.
Prognosis
The prognosis for individuals with tachyarrhythmia varies widely. Some people may experience occasional episodes with minimal impact on their daily lives, while others may have more frequent or severe episodes requiring ongoing treatment. With appropriate management, many individuals can lead normal, active lives. However, untreated tachyarrhythmia can lead to complications such as heart failure or stroke.
Etiology
Tachyarrhythmia can result from various factors, including heart disease, high blood pressure, electrolyte imbalances, or congenital heart defects. Other potential causes include stress, excessive caffeine or alcohol consumption, and certain medications. In some cases, the exact cause may not be identifiable.
Epidemiology
Tachyarrhythmia is a common condition, affecting millions of people worldwide. It can occur at any age but is more prevalent in older adults. The risk of developing tachyarrhythmia increases with age and is higher in individuals with underlying heart conditions or other risk factors such as obesity or diabetes.
Pathophysiology
The heart's electrical system controls the heartbeat, and tachyarrhythmia occurs when there is a disruption in this system. This disruption can lead to rapid electrical signals that cause the heart to beat faster than normal. The specific mechanisms can vary depending on the type of tachyarrhythmia, such as atrial fibrillation, supraventricular tachycardia, or ventricular tachycardia.
Prevention
Preventing tachyarrhythmia involves managing risk factors and maintaining a healthy lifestyle. This includes regular exercise, a balanced diet, avoiding excessive caffeine and alcohol, and managing stress. Regular medical check-ups can help detect and address potential issues early. For those with known risk factors, medications or procedures may be recommended to prevent episodes.
Summary
Tachyarrhythmia is a condition characterized by an abnormally fast heart rate due to irregular electrical activity in the heart. It can present with various symptoms and requires a comprehensive approach for diagnosis and management. While the condition can be serious, effective treatments are available, and many individuals can manage their symptoms and lead healthy lives.
Patient Information
If you suspect you have tachyarrhythmia, it's important to understand the condition and its potential impact on your health. Symptoms like palpitations, dizziness, or chest pain should not be ignored. Diagnosis typically involves an ECG and other tests to assess heart function. Treatment options range from lifestyle changes to medications and procedures, depending on the severity of the condition. With proper management, many people with tachyarrhythmia can maintain a good quality of life.
References
- Rodriguez LM, de Chillou C, Schläpfer J, et al. Age at onset and gender of patients with different types of supraventricular tachycardias. Am J Cardiol. 1992;70(13):1213–1215.
- Akhtar M, Jazayeri MR, Sra J, Blanck Z, Deshpande S, Dhala A. Atrioventricular nodal reentry. Clinical, electrophysiological, and therapeutic considerations. Circulation. 1993;88(1):282–295.
- Chauhan VS, Krahn AD, Klein GJ, Skanes AC, Yee R. Supraventricular tachycardia Med Clin North Am. 2001;85(2):193–223.
- Mark DG, Brady WJ, Pines JM. Preexcitation syndromes: diagnostic considerations in the ED. Am J Emerg Med. 2009;27(7):878–888.
- Wellens HJ, Brugada P. Mechanisms of supraventricular tachycardia. Am J Cardiol. 1988;62(6):10D–15D.
- Kastor JA. Multifocal atrial tachycardia. N Engl J Med. 1990;322(24):1713–1717.
- Roberts-Thomson KC, Kistler PM, Kalman JM. Focal atrial tachycardia II: management. Pacing Clin Electrophysiol. 2006;29(7):769–778.
- Lessmeier TJ, Gamperling D, Johnson-Liddon V, et al. Unrecognized paroxysmal supraventricular tachycardia. Potential for misdiagnosis as panic disorder. Arch Intern Med. 1997;157(5):537–543.
- Fenelon G, Wijns W, Andries E, Brugada P. Tachycardiomyopathy: mechanisms and clinical implications. Pacing Clin Electrophysiol. 1996;19(1):95–106