After 2010, there was a decrease in serotypes 14, 1, 23F and 5 and an increase in serotypes 3, 12F, 11A and 8, which were not present in the vaccine. CONCLUSIONS: The present study noted the increase in serotypes 3, 12F, 11A and 8 after vaccination. [ncbi.nlm.nih.gov]

• Fatigue

  A 62-year-old splenectomized woman was admitted because of upper respiratory tract symptoms, general fatigue, and purpura. [ncbi.nlm.nih.gov]

  She also endorses shortness of breath and severe fatigue. Her vital signs are as follows: T 38.5 C, HR 98, BP 110/66, RR 18, SpO2 94% on room air. [step1.medbullets.com]

  After incubation the infected individual will begin to acquire symptoms such as a high fever, chills, cough, sore throat, chest pains, body aches, fatigue, rapid breathing, and maybe even nausea/vomiting. (10 and 11). [austincc.edu]

  Recent estimates suggest 27% of community-acquired pneumonia cases are S. pneumoniae (Said, 2013) Often develops as a secondary pneumonia during upper respiratory tract infections Abrupt onset of fever, shaking chills, cough, dyspnea, tachypnea, and fatigue [arupconsult.com]

• Nausea

  Pneumococcal meningitis People with pneumococcal meningitis often have: high fever headache stiff neck nausea and vomiting photophobia (discomfort when looking at light). [sahealth.sa.gov.au]

  You may first have a severe shaking chill which is usually followed by: High fever Cough Shortness of breath Rapid breathing Chest pains Other symptoms may include: Nausea Vomiting Headache Tiredness Muscle aches Diagnosis Your healthcare provider can [medicinenet.com]

  After incubation the infected individual will begin to acquire symptoms such as a high fever, chills, cough, sore throat, chest pains, body aches, fatigue, rapid breathing, and maybe even nausea/vomiting. (10 and 11). [austincc.edu]

  Her symptoms are associated with neck stiffness and nausea. Physical examination is significant for nuchal rigidity and an inability to extend at the knee while the hips are flexed at 90 °. [step1.medbullets.com]

• Left Ventricular Dysfunction

  Both children fully recovered, and none of them developed constrictive pericarditis, although 1 case presented a transient secondary left ventricular dysfunction. [ncbi.nlm.nih.gov]

• Refractory Shock

  He progressed into hypotension, disseminated intravascular coagulation and refractory shock despite resuscitation and early antibiotic commencement. [ncbi.nlm.nih.gov]

• Headache

  Diagnosis Indications for Testing Fever or chills, cough, shortness of breath, tachypnea, tachycardia, infiltrates on chest x-ray, suggesting pneumonia Fever, neck pain and stiffness, headache, suggesting meningitis Fever or chills, hypotension, tachycardia [arupconsult.com]

  If the infection spreads to the brain and spinal cord, it can cause pneumococcal meningitis, characterised by a stiff neck, fever, confusion, and headaches. Pneumococcal infection is responsible for 1-2 million infant deaths worldwide, every year. [creative-diagnostics.com]

  Snapshot A 56-year-old man presents to the emergency department for a severe headache, generalized malaise, and fatigue. Her symptoms are associated with neck stiffness and nausea. [step1.medbullets.com]

• Rabies

  Blood cultures are positive in only 20% to 25% of all pneumonia cases that are caused by S. pneumonia making it a challenging diagnosis for the clinician.[1][2][3] Etiology S. pneumonia was first isolated from the saliva of a patient with rabies in 1881 [ncbi.nlm.nih.gov]

  The bacterium, also called pneumococcus, was first isolated by Pasteur in 1881 from the saliva of a patient with rabies. [cdc.gov]

We acknowledge that our diagnosis is presumptive since cultures from sterile sites (ie, blood) were negative; an extensive workup for other etiologies was negative. [journals.lww.com]

Significant in her medical history was a parathyroidectomy 7 years ago for hyperparathyroidism, discovered following metabolic workup for nephrolithiasis; serum parathyroid hormone and calcium levels returned to normal. [liebertpub.com]

[…] prevention. 17, 18 A metabolic workup including blood and urine laboratory tests are indicated. [journals.sagepub.com]

Blood culture was not a part of the standard diagnostic workup in our study. However, no more than 20% of pediatric patients with pneumococcal CAP usually have positive blood culture results [35–37]. [academic.oup.com]

Nonetheless, concern has been raised more recently about an increase that has since been observed in the severity of asthma symptoms and the need for more intensive care management. [3] (See Prognosis, Workup, Treatment, and Medication .) [emedicine.medscape.com]

• Pulmonary Infiltrate

  Serotype 3-associated pneumonia may develop a wider pulmonary infiltrative shadow, a prolonged therapeutic or hospitalization course, and a poor outcome. [ncbi.nlm.nih.gov]

AOM, and post-treatment visits), based on their phenotypic and genotypic characteristics performed by analyses of serotype, antibiotic susceptibility patterns and multilocus sequence typing. [ncbi.nlm.nih.gov]

Other diagnostic tools include urinary antigen rapid tests for teichoic acid (polysaccharide of the cell wall of the bacteria).4 Treatment Treatment will usually include a broad-spectrum cephalosporin, and often vancomycin, until results of antibiotic [quidel.com]

Treatment Antibiotics are the first line of treatment for bacterial infections, and are effective against pneumococcus. However, treatment of pneumococcal infections is dependent on the strain that a patient is infected with. [news-medical.net]

However, complete staghorn calculus is rare in polycystic kidney disease and predicts a gloomy prognosis of kidney. [semanticscholar.org]

Treatment and prognosis Staghorn calculi need to be treated surgically, usually PCNL (percutaneous nephrolithotomy) +/- ESWL (extracorporeal shockwave lithotripsy) and the entire stone removed, including small fragments, as otherwise, these residual fragments [radiopaedia.org]

Laboratory evaluation.Table 3 shows the laboratory data by etiologic group. [academic.oup.com]

We review the literature for similar cases due to S. pneumoniae in the pediatric population and discuss the etiology and treatment of purpura fulminans. [ncbi.nlm.nih.gov]

Applicable To Bronchopneumonia due to S. pneumoniae Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]

KEYWORDS: Streptococcus pneumoniae (pneumococcus); Infectious disease epidemiology; modelling; spread of disease; vaccine policy development [ncbi.nlm.nih.gov]

Data Surveillance systems overview for 2017 Publication Generic protocol on enhanced surveillance for invasive pneumococcal disease at the EU/EEA level Publication Invasive pneumococcal disease - Annual Epidemiological Report for 2016 Data Surveillance [ecdc.europa.eu]

Isolation Clinical specimen - human, Portugal, 1996 References representative strain of the Pneumococcal Molecular Epidemiology Network (PMEN) Sa-Leao R, et al. [atcc.org]

Useful For Suggests clinical disorders or settings where the test may be helpful Rapid diagnosis of pneumococcal pneumonia Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Streptococcus [mayocliniclabs.com]

Pathophysiology The precise pathophysiology of pneumococcal HUS has not been determined. However, there is evidence of a role for the Thomsen–Friedenreich (TF) cryptantigen [ 39 ]. [link.springer.com]

"Intravascular hemolysis and the pathophysiology of sickle cell disease". Journal of Clinical Investigation. 127 (3): 750–760. doi:10.1172/JCI89741. ISSN 0021-9738. [en.wikipedia.org]

Centers for Disease Control and Prevention. 2015. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Streptococcus pneumoniae, 2015. Centers for Disease Control and Prevention. [cdc.gov]

Prevnar 13® is the trade name in the United States, Canada, and Taiwan. 1 Centers for Disease Control and Prevention. Pneumonia can be prevented - vaccines can help. http://www.cdc.gov/features/pneumonia/. [pfizer.com]

Control and Prevention, State Key Laboratory for Infectious Disease Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing 102206, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, [ncbi.nlm.nih.gov]

[…] of Vaccine-Preventable Diseases Ask the Experts about PCV13 and PPSV23 CDC experts answer your clinical questions (Immunization Action Coalition) Use of Vaccines to Prevent Meningitis in Persons with Cochlear Implants Updated Apr 2012 Facts about pneumococcal [web.archive.org]

Prevention Pneumococcal Diseases 1 3 Completed Prevention Bacterial Infections / Neisseria Meningitidis / Virus Diseases 1 3 Not Yet Recruiting Prevention Infections, Pneumococcal 1 3 Recruiting Prevention Infections, Pneumococcal 3 3 Recruiting Prevention [drugbank.ca]