However, the effect on fatigue as major complaint in chronic fatigue patients without excessive daytime sleepiness, is not fully understood nor explored. [ncbi.nlm.nih.gov]

RSIA requires a railroad to consider the need to include in its fatigue management plan “opportunities for identification, diagnosis, and treatment of any medical condition that may affect alertness or fatigue, including sleep disorders.” ( Id. at section [federalregister.gov]

Complications may include: Daytime fatigue and sleepiness. The repeated awakenings associated with obstructive sleep apnea make normal, restorative sleep impossible. [mayoclinic.org]

We report a patient with anti-muscle kinase receptor MG with severe OSA and hypoventilation that resolved upon successful treatment of MG despite a 60-lb weight gain. [ncbi.nlm.nih.gov]

This may be due to allergies and seasonal weight gain (many people get heavier in the winter). [tuck.com]

gain) Excessive daytime sleepiness [stanfordhealthcare.org]

Symptoms of OSAS, including excessive sleepiness, nocturnal awakenings, and morning headaches, improve with treatment. [clinicaladvisor.com]

Frequent nocturnal awakening in early life is associated with nonatopic asthma in children. Eur Respir J. 34, 1288–95 (2009). 19. Shen, T. C. et al. [nature.com]

Patients often complain of snoring, Gasping or choking, frequent nocturnal awakenings, early morning headaches, poor concentration and coordination, anxiety, irritability, and insomnia, yet many patients are unaware of these symptoms and disease onset [intechopen.com]

Association of obstructive sleep apnoea with subclinical coronary atherosclerosis. Atherosclerosis. 2013 ; 231 :191–197. doi: 10.1016/j.atherosclerosis.2013.09.011. Crossref Medline Google Scholar 7. [circ.ahajournals.org]

Nocturnal oxygen desaturation correlates with the severity of coronary atherosclerosis in coronary artery disease. Chest 2003 ;124: 936 - 941 38. Becker HF, Jerrentrup A, Ploch T, et al. [doi.org]

Associated conditions include obesity; acromegaly; myxedema; micrognathia; myotonic dystrophy; adenotonsilar dystrophy; and neuromuscular diseases. [icd9data.com]

Before you have surgery, tell your doctor if you have obstructive sleep apnea or symptoms related to obstructive sleep apnea. If you have obstructive sleep apnea symptoms, your doctor may test you for obstructive sleep apnea prior to surgery. [mayoclinic.org]

[…] to obstuctive sleep apnea Acute respiratory failure from obstuctive sleep apnea Adult obstructive sleep apnea Complex sleep apnea Obstructive sleep apnea Obstructive sleep apnea of adult Obstructive sleep apnea of child Obstructive sleep apnea syndrome [icd9data.com]

About one half of patients who have essential hypertension have obstructive sleep apnea, and about one half of patients who have obstructive sleep apnea have essential hypertension. [ncbi.nlm.nih.gov]

Sleep apnea currently affects more than 18 million American adults. [medicaldaily.com]

Eligibility: (1) Patients: controls, snoring or OSA patients (2) Intervention: neuromuscular evaluation of the palate and/or uvula (3) Comparison: differences between controls, snoring and OSA patients (4) Outcomes: neuromuscular outcomes (5) Study design [ncbi.nlm.nih.gov]

Snoring alone had no impact on mortality in any of the age groups ( Table 2 ). [doi.org]

Be sure to talk to your doctor if you experience loud snoring, especially snoring that's punctuated by periods of silence. [mayoclinic.org]

Loud snoring is a telltale symptom of OSA. Snoring is caused by air squeezing through the narrowed or blocked airway. Not everyone who snores has sleep apnea though. [nlm.nih.gov]

OSA related symptoms included loud snoring, apneas, awakenings with gasping breaths, enuresis, and daytime sleepiness. [ncbi.nlm.nih.gov]

Loud snoring is a telltale symptom of OSA. Snoring is caused by air squeezing through the narrowed or blocked airway. Not everyone who snores has sleep apnea though. [nlm.nih.gov]

Be sure to talk to your doctor if you experience loud snoring, especially snoring that's punctuated by periods of silence. [mayoclinic.org]

Simple queries of the patient or bed-partner for the symptoms and signs of the disorder, namely, loud snoring, observed apneas, and daytime sleepiness, would help identify those in need of further diagnostic evaluation. [doi.org]

Chronic nasal congestion. Obstructive sleep apnea occurs twice as often in those who have consistent nasal congestion at night, regardless of the cause. This may be due to narrowed airways. Smoking. [mayoclinic.org]

This can be the result of an upper respiratory infection that causes nasal congestion, along with swelling of the throat, or tonsillitis that temporarily produces very enlarged tonsils. [sciencedaily.com]

congestion – OSA occurs more often in people with nasal congestion, such as a deviated septum, where the tissue in the nose that divides the two nostrils is bent to one side, or nasal polyps, which may be a result of the airways being narrowed Treating [nhs.uk]

Odds ratios for apnoea-hypopnoea index, body mass index, sex, age, and hypertension Fig 1. [doi.org]

We aimed to clarify the association between OSA and hypertension, including essential and medication-resistant hypertension. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was followed. [ncbi.nlm.nih.gov]

The combination of hypoxaemia and partial arousal with each apnoea or hypopnoea is accompanied by a surge of adrenergic activity with consequent tachycardia and transient systemic hypertension. [academic.oup.com]

Activation of the sympathetic nervous system, by both hypoxia and arousal, may induce tachycardia and peripheral vasoconstriction, further increasing ventricular afterload (67). [onlinejacc.org]

Heart rates often change during apneic episodes, with relative bradycardia occurring during airway obstruction followed by tachycardia during arousals. Specific cranio-facial and oropharyngeal features also predispose a person to develop OSA. [todaysgeriatricmedicine.com]

Cardiovascular Disease in Obstructive Sleep Apnea • Vagal stimulation causes bradycardia • Bradycardia and hypoxia provoke serious cardiac rhythm disturbances i.e. premature beats asystole, ventricular tachycardia, cardiac arrest. 26. [slideshare.net]

[…] suggested an increased risk for coronary artery disease/myocardial ischemia, 13, 14 cerebrovascular accidents, 15, 16 and cardiomyopathy. 15, 17 Brady- and tachyarrhythmias may occur with increased frequency in patients with SDB, 18, 19 and ventricular tachycardia [clinical.diabetesjournals.org]

Subjective assessments of clinical symptoms/signs, including snoring visual analog scale (VAS), nasal obstruction, and mouth breathing, were recorded. [ncbi.nlm.nih.gov]

Common symptoms of obstructive sleep apnea in children may include: Snoring Daytime cognitive and behavior problems, including problems paying attention, easy distractibility, aggressive behavior and hyperactivity Mouth breathing Enlarged tonsils and [stanfordhealthcare.org]

Loud or noisy breathing, snoring, or mouth breathing during sleep Brief pauses in breathing during sleep or difficulty breathing during sleep Restless sleep (i.e., lots of tossing and turning) Sweating heavily during sleep Bedwetting Sleeping in odd positions [my.clevelandclinic.org]

Symptoms of Obstructive Sleep Apnea (OSA) are: snoring, restless/disturbed sleep, frequent partial or total wakenings and daytime mouth breathing. [ds-health.com]

Snoring, mouth breathing, and obstructive sleep apnea (OSA) often prompt parents to seek medical attention for their children. [aafp.org]

The facial numbness was temporary in 4 (57.1%), and permanent in one case (14.3%). Conclusion: Our surgical results in MMA is compatible with literature data. [ncbi.nlm.nih.gov]

People with obstructive sleep apnea may also complain of memory problems, morning headaches, mood swings or feelings of depression, and a need to urinate frequently at night (nocturia). [mayoclinic.org]

“We're talking about car accidents in the daytime, lost productivity at work, mood swings, waking up feeling groggy and falling asleep in class.” [hopkinsmedicine.org]

swings Spotting OSA-Related Eye Problems Ophthalmologists can spot signs of visual conditions that may be linked with sleep apnea, said Dr. [aao.org]

They include: breathing stopping and starting making gasping, snorting or choking noises waking up a lot loud snoring During the day, you may also: feel very tired find it hard to concentrate have mood swings have a headache when you wake up Information [nhs.uk]

Sexual dysfunction severity in aging men is due to modifiable risk factors [ 70 ]. [transbiomedicine.com]

Adverse effects of hypersomnolence, such as loss of employment and sexual dysfunction, can affect families considerably. [msdmanuals.com]

dysfunction Headaches People with central sleep apnea more often report recurrent awakenings or insomnia, although they may also experience a choking or gasping sensation upon awakening. [my.clevelandclinic.org]

Daytime symptoms • Decreased vigilance • Morning confusion • Personality and mood changes, including depression and anxiety • Sexual dysfunction, including impotence and decreased libido • Gastroesophageal reflux • Hypertension • Depression 18. [slideshare.net]

Since people with sleep apnea tend to be sleep deprived, they may suffer from sleeplessness and a wide range of other symptoms such as difficulty concentrating, depression, irritability, sexual dysfunction, learning and memory difficulties, and falling [sleepfoundation.org]

A 36-year-old active duty male with migraine headaches presented for evaluation of poorly controlled hypertension. [ncbi.nlm.nih.gov]

There is a strong association between OSA and headache. In particular, there is a “sleep apnea headache” described as a recurrent morning headache, with resolution after effective treatment of sleep apnea. [link.springer.com]

Irritability/personality change. Nocturia. Decreased libido. Symptoms such as personality change, episodes of apnoea, irritability and restlessness at night may be better elicited by taking a history from a partner. [patient.info]

Ask your doctor about any sleep problem that leaves you chronically fatigued, sleepy and irritable. Excessive daytime drowsiness may be due to other disorders, such as narcolepsy. [mayoclinic.org]

Common adverse effects of CPAP and MADs included oral or nasal dryness, irritation, and pain, among others. In cohort studies, there was a consistent association between AHI and all-cause mortality. [ncbi.nlm.nih.gov]

OSA can cause children to be tired, irritable or hyperactive during the day and to perform below their potential at school. [childrenshospital.org]

A 64-year-old woman was referred to the department of otolaryngology because of daytime sleepiness and morning headaches. The patient refused polysomnographic evaluation because of claustrophobia. [ncbi.nlm.nih.gov]

People with obstructive sleep apnea may also complain of memory problems, morning headaches, mood swings or feelings of depression, and a need to urinate frequently at night (nocturia). [mayoclinic.org]

In many cases it leads to debilitating daytime sleepiness, morning headaches, depression, and a general sense of unwellness. [sleepapnea.org]

Typical symptoms include snoring, not feeling refreshed on waking, day-time sleepiness, altered mood and morning headaches. [southerncross.co.nz]

Neither patient exhibited daytime somnolence, although both were subsequently found to have severe obstructive sleep apnea. [ncbi.nlm.nih.gov]

disturbance (difference -2.8, -4.7 to -0.9, P 0.01). [ncbi.nlm.nih.gov]

In conclusion, didgeridoo playing improved daytime sleepiness in patients with moderate snoring and obstructive sleep apnoea and reduced sleep disturbance in their partners. [doi.org]

The combination of sleep disturbance and oxygen starvation can result in multiple problems, including automobile accidents, hypertension, heart disease, and mood and memory problems. OSA affects approximately 20 million Americans. [holyname.org]

Six months later, severe hypoxemia without hypercapnia was noted. Contrast transthoracic echocardiography showed right-to-left shunt through a patent foramen ovale. [ncbi.nlm.nih.gov]

The respiratory pauses may induce hypercapnia or hypoxia. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. [icd9data.com]

References: [5] [3] Pathophysiology Obstruction of the upper airways apnea partial pressure of oxygen in arterial blood ( PaO 2 ), partial pressure of carbon dioxide in arterial blood ( PaCO 2, also known as hypercapnia ) Hypoxic pulmonary vasoconstriction [amboss.com]

Neural responses to hypoxia and hypercapnia have not been well studied in children with obstructive sleep apnea and underlying syndromes. [emedicine.com]

Obesity hypoventilation syndrome or the Pickwickian syndrome • Defined by morbid obesity (body mass index greater than 40 kg/m2) and chronic hypoventilation with hypercapnia (PaCO2 greater than 45 mmHg) during wakefulness. • Characteristic findings observed [slideshare.net]