Presentation
Herpes simplex virus 1 infection (although unusual) should be considered in patients with systemic lupus erythematosus with an atypical clinical presentation. [ncbi.nlm.nih.gov]
People with a history of cold sores may shed the virus in their saliva even without a blister being present. [sahealth.sa.gov.au]
Entire Body System
- Dentist
Prior to the use of protective gloves for all patients (“universal precautions”), this was a common infection of dentists, dental hygienists, physicians, and nurses. [viceprovost.tufts.edu]
[…] population) Etiology Direct contact with infected secretions through a break in the skin, e.g., torn cuticle Main groups: Children ; (via sucking of thumb/fingers (may have a history of labial herpes ) Health care workers exposed to oral secretions (e.g., dentists [amboss.com]
- Hodgkin Lymphoma
This is particularly advantageous when designing clinical applications for a chronic disease such as CLL or non-Hodgkin lymphoma for which treatment would likely require repeated vector administration over long periods of time. [bloodjournal.org]
Skin
- Flushing
After an Exposure Incident Occurs: Immediate Action by Route of Exposure Mucous Membranes (eye(s), nose, mouth): If contaminated material is splashed or sprayed, immediately flush the eyes, nose and nasal cavities with running water for at least 15 minutes [viceprovost.tufts.edu]
Eyes
- Blepharitis
HSV infection may cause other ocular diseases, including blepharitis/dermatitis, conjunctivitis, and dendritic epithelial keratitis. Post-exposure The healthcare provider will determine the course of treatment. [viceprovost.tufts.edu]
HSV infection may cause other ocular diseases, including blepharitis/dermatitis, conjunctivitis, dendritic epithelial keratitis, and corneal ulceration Footnote 6. [canada.ca]
- Blurred Vision
Symptoms of herpes keratitis include: eye pain and redness discharge or excess tears in the eye blurred vision sensitivity to light a gritty feeling in the eye If you’re living HSV and notice these symptoms, contact a doctor or eye doctor as soon as possible [healthline.com]
- Photophobia
Physical examination revealed a temperature of 37.7°C (99.8°F), meningism, and photophobia. The patient's hair, skin, oral and genital mucosae, joints, and extremities were normal. External and funduscopic eye examinations were normal. [nejm.org]
Urogenital
- Syphilitic Chancre
chancre or chancroid See “Diagnostics” and "Treatment" below. [amboss.com]
Workup
Previous workup of these episodes included a negative electroencephalogram and CT scan and negative cerebrospinal fluid, serologic, and skin tests for relevant microbial pathogens. [nejm.org]
Microbiology
- Chlamydia
This finding is not consistent with the assumption that diabetes leads to HSV-1 infection, because among several pathogens thought to be involved in the pathogenesis of cardiovascular diseases, only HSV-1 infection, i.e., not Chlamydia pneumonia, cytomegalovirus [care.diabetesjournals.org]
カテゴリ 感染症 階層分類 感染症疾患 [BR: jp08401 ] ウイルス感染症 dsDNAウイルスによる感染症 H00365 単純ヘルペスウイルス感染症 ICD-11 による疾患分類 [BR: jp08403 ] 01 Certain infectious or parasitic diseases Predominantly sexually transmitted infections Sexually transmissible infections due to chlamydia [kegg.jp]
Prevalence of chlamydia trachomatis and herpes simplex virus type 2: Results from the 2009 to 2011 Canadian Health Measures Survey. [bmcinfectdis.biomedcentral.com]
- Human Herpesvirus 8
"Reactivation of and Primary Infection with Human Herpesvirus 8 among Solid-Organ Transplant Recipients." The Journal of Infectious Diseases 185.9 (2002): 1238-243. [microbewiki.kenyon.edu]
Other Pathologies
- Intranuclear Inclusion Bodies
Gov't MeSH terms Animals Base Sequence Gene Expression Regulation, Viral Genes, Viral* HeLa Cells Herpes Simplex/virology Herpesvirus 1, Human/genetics Herpesvirus 1, Human/physiology* Humans Intranuclear Inclusion Bodies/metabolism Mice Nuclear Matrix-Associated [ncbi.nlm.nih.gov]
Treatment
Prompt recognition and treatment can be life-saving in the care of patients with herpes simplex-1 virus encephalitis, the most commonly identified cause of sporadic encephalitis worldwide. [ncbi.nlm.nih.gov]
Prognosis
Outcomes and prognosis The reduction in HSE mortality has led to a paradoxical situation. There are without doubt more survivors, but many may suffer from permanent neurological and/or psychological deficits, for example amnesia (memory loss). [encephalitis.info]
What should you tell the family about the patient's prognosis? Complications of severe oral herpes include dysphagia, severe pain, and inability to take oral medications. [infectiousdiseaseadvisor.com]
Etiology
Thus our cases represent two examples of chronic encephalitis associated with a seizure disorder, where a definitive viral etiology was documented by PCR. [ncbi.nlm.nih.gov]
PCR for the existence of both bacterial and viral etiological agent should be performed along with routine CSF detailed report test to confirm the etiology. [oatext.com]
For genital herpes during pregnancy, see congenital herpes simplex virus infection Herpetic gingivostomatitis Etiology : severe manifestation of an (often primary) HSV-1 infection Mainly in children (∼ 1–6 years), but also immunocompromised patients [amboss.com]
Epidemiology
A systematic review of the epidemiology and interaction of herpes simplex virus types 1 and 2 K J Looker, G P Garnett Department of Infectious Disease Epidemiology, Imperial College London, UK Correspondence to: K J Looker Department of Infectious Disease [sti.bmj.com]
Modern Epidemiology, 323 -325, Little, Brown, and Company Boston 1986. ↵ Hosmer D. W., Lemeshow S. Confidence interval estimation of interaction. Epidemiology, 3 : 452 -456, 1992. ↵ Shillitoe E. J., Silverman S., Jr. [cancerres.aacrjournals.org]
After the data became available, the Epidemiology and Surveillance Branch analyzed the data and developed the manuscript. [jamanetwork.com]
Both are closely related but differ in epidemiology. HSV-1 is traditionally associated with orofacial disease (see the image below), while HSV-2 is traditionally associated with genital disease. [emedicine.medscape.com]
Pathophysiology
Abstract Controversy still surrounds both the etiology and pathophysiology of vestibular neuritis (VN). [ncbi.nlm.nih.gov]
Pathophysiology, clinical consequences, and medical therapy: part II. [care.diabetesjournals.org]
Prevention
Although Us3 did not detectably prevent energy stress-induced AMPK activation, it enforced mTORC1 activation despite the presence of activated AMPK. [ncbi.nlm.nih.gov]
Image courtesy Public Health Image Library (PHIL), Department of Health and Human Services, Centers for Disease Control and Prevention (CDC-USA) Dr Herrmann. [sahealth.sa.gov.au]