Primary bilateral non-Hodgkin's lymphoma of the adrenal gland is a rare presentation with <200 reported cases. [ncbi.nlm.nih.gov]

• Anemia

  Despite identified limitations in the grading and reporting of treatment-related anemia, the results confirm a relatively high incidence of mild-to-moderate anemia. [ncbi.nlm.nih.gov]

  A low red blood cell count is known as anemia. Anemia can lead to fatigue, chest pain, and more serious complications. Platelets are structures in the blood that help stop bleeding. A low platelet cell count is known as thrombocytopenia. [chemotherapy.com]

  The purpose of the guidelines is to operationalize the evaluation and treatment of anemia in cancer patients and to enable patients and clinicians to evaluate treatment options in the context of risks and benefits. [doi.org]

• Hodgkin Lymphoma

  KEYWORDS: Non - Hodgkin’s lymphoma; hemihepatectomy; hepatic DLBCL; treatment [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

  Other tumours reported at increased incidence, in particular among Hodgkin's disease patients, for whom a carcinogenic effect of chemotherapy seems plausible, are non-Hodgkin's lymphoma and lung cancer. [informahealthcare.com]

• Weakness

  When side effects of chemotherapy do occur, here are some of the most common: Anemia Appetite Changes Bleeding Problems Constipation Diarrhea Fatigue (Feeling weak and very tired) Hair Loss (Alopecia) Infection Memory Changes Mouth and Throat Changes [virtua.org]

  Some chemo drugs can also cause: pain weakness numbness tingling in the hands and feet (peripheral neuropathy) Your muscles may feel tired, achy, or shaky. And your reflexes and small motor skills may slow down. [healthline.com]

  […] blood pressure Decreased appetite Diarrhea Hydroxyurea (Hydrea): usually given orally Decrease in blood cell counts Nausea and vomiting Diarrhea Mercaptopurine (6-MP, Purinethol): usually given orally Nausea and vomiting Decreased appetite Tiredness and weakness [childrensnational.org]

  When drugs lower the levels of healthy blood cells, you’re more likely to get infections, bruise or bleed easily, and feel very weak and tired. Your healthcare team will check for low levels of blood cells. [nationalbreastcancer.org]

  […] memory (some people refer to this as ‘chemo brain’) emotional changes blood cell disorders, which may result in anaemia, dizziness, shortness of breath and increased risk of infection effects on the nervous system, such as tingling, burning or muscle weakness [canceraustralia.gov.au]

• Lymphedema

  the side effects of chemotherapy include: easy bruising and excessive bleeding diarrhea dry mouth mouth sores fatigue a fever hair loss a loss of appetite nausea vomiting weight loss pain from nerve damage infections anemia constipation neuropathy lymphedema [healthline.com]

• Malaise

  A low red blood cell count (anemia) causes fatigue, paleness, dizziness, shortness of breath and malaise. Fatigue Fatigue makes a person feel more tired than usual and can interfere with daily activities and sleep. [cancer.ca]

  In the elderly, symptoms of cholecystitis may be nonspecific (eg, anorexia, vomiting, malaise, weakness), and fever may be absent. [msdmanuals.com]

• Loss of Appetite

  Chemotherapy commonly causes nausea, vomiting, loss of appetite, weight loss, fatigue, and low blood cell counts that lead to anemia and increased risk of infections. [merckmanuals.com]

  Some common side effects of chemotherapy that can occur in the days or weeks after treatment include: fatigue (tiredness) nausea, vomiting and loss of appetite pain or soreness, such as headaches, muscle pain or nerve pain sores in the throat or mouth [canceraustralia.gov.au]

  Side effects Chemotherapy is known for causing several side effects, which include: Nausea Vomiting Fatigue Hair loss Anemia Bruising Bleeding Loss of appetite Sleeping problem Constipation Depression To minimize the side effects, most doctors administer [docdoc.com.sg]

  Other side effects of docetaxel include low platelets which can result in bleeding (1%), anemia (5%), reduced heart function (10%), hair loss (65%), diarrhea (32%), nail changes (30%), loss of appetite (20%), shortness of breath (15%), and fluid retention [pcf.org]

  After treatment with chemotherapy, you may lose your hair and have other side effects, such as loss of appetite, nausea, vomiting, diarrhea, or mouth sores. [northshore.org]

• Sore Mouth

  Sore mouth A sore mouth (also called stomatitis or oral mucositis) happens because of chemotherapy’s effect on cells inside the mouth. Many drugs can cause a sore mouth, but it happens more often when higher doses of drugs are used. [cancer.ca]

  This can cause a range of unpleasant side effects, such as: feeling tired most of the time feeling and being sick hair loss an increased risk of getting infections a sore mouth dry, sore or itchy skin diarrhoea or constipation Many of these side effects [nhs.uk]

  If you have a sore mouth and are not eating properly, chilled drinks such as smoothies from the blender can be good. Early menopause Chemotherapy can reduce your oestrogen levels and cause periods to stop, either temporarily or altogether. [bcna.org.au]

  Mouth sores: Mouth sores, also referred to as mucositis, are caused by an inflammatory reaction of the mucous lining of the gastrointestinal tract. They can also affect chewing, swallowing and taste, and can be managed with pain medication. [mesothelioma.com]

• Metallic Taste

  Eating soft mints can help get rid of the metallic taste that you may experience. If you have a sore mouth and are not eating properly, chilled drinks such as smoothies from the blender can be good. [bcna.org.au]

  You might even have a metallic taste in the mouth, or a yellow or white coating on your tongue. Food may taste unusual or unpleasant, leading to unintentional weight loss from not eating. [healthline.com]

  Changes in taste and smell Some chemotherapy drugs can affect taste buds causing changes in taste. For example, you may find that meats have a metallic taste. Even foods that you normally crave, such as sweet or salty snacks, can taste bad. [cancer.ca]

  Changes in taste – many people say food tastes bland. Others describe a metallic taste, or find that food tastes more salty or bitter than usual. Skin changes including rashes – some drugs make your skin photosensitive (more sensitive to sunlight). [lymphoma-action.org.uk]

• Alopecia

  There were no differences between men and women with regard to body image in respect of degree of alopecia, but the body image of the male and female patients who had partial or complete alopecia was lower than that in patients who had no alopecia; psychological [ncbi.nlm.nih.gov]

  Few dermatologic conditions carry as much emotional distress as chemotherapy-induced alopecia (CIA). The prerequisite for successful development of strategies for CIA prevention is the understanding of the pathobiology of CIA. [doi.org]

  When side effects of chemotherapy do occur, here are some of the most common: Anemia Appetite Changes Bleeding Problems Constipation Diarrhea Fatigue (Feeling weak and very tired) Hair Loss (Alopecia) Infection Memory Changes Mouth and Throat Changes [virtua.org]

• Amenorrhea

  After ABVD or 4–6 cycles of CHOP the risk of permanent amenorrhea has been reported to be below 20% [11] Lee SJ, Schover LR, Partridge AH, Patrizio P, Wallace WH, Hagerty K, et al. [doi.org]

  Two FSH levels in the menopausal range measured at least one month apart and associated with amenorrhea/oligomenorrhea and low estradiol levels are strongly suggestive of ovarian failure. [medscape.com]

  Disease Regimen % Low Sperm Count Hodgkin's MOPP 85% Hodgkin's ABVD 0 Testes Cancer Cisplatin, vinblastine, bleomycin 14-28% Sarcoma Doxorubicin + Cyclophosphamide 65% Disease Regimen % Amenorrhea Ovarian Cancer Cisplatin, Vincristine, methotrexate, etoposide [cancersupportivecare.com]

  […] particularly in males) an alteration of reproductive functions, with: azoospermia (frequency up to 100% of cases, sometimes reversible after therapy termination; it imposes a beforehand semen collection and preservation in young patients); secondary amenorrhea [medichub.ro]

• Secondary Amenorrhea

  amenorrhea (it occurs at 3-4 months after the chemotherapy; recovery is variable and it depends on the age when the cytostatic treatment was started – in young women it can reach over 50% of cases). [medichub.ro]

  Secondary amenorrhea after Hodgkin's lymphoma is influenced by age at treatment, stage of disease, chemotherapy regimen, and the use of oral contraceptives during therapy: A report from the German Hodgkin's Lymphoma Study Group. [doi.org]

[…] acute cholecystitis MRI without contrast is useful for eliminating radiation exposure in pregnant women when ultrasonography has not yielded a clear diagnosis Contrast agents should not be used in patients on dialysis unless absolutely necessary See Workup [emedicine.medscape.com]

This study changed the workup of all people with advanced gastric cancer since all people with advanced gastric cancer must now undergo HER‐2 testing before the initiation of any chemotherapy and, in the absence of contraindications, be treated with trastuzumab [doi.org]

• Neutropenia

  We could perform sequential chemotherapy immediately while paying attention to grade 4 neutropenia. KEYWORDS: Neutropenia; Non-small cell lung cancer; Postoperative adjuvant chemotherapy; Sequential chemotherapy; Tegafur-uracil [ncbi.nlm.nih.gov]

  One patient underwent an elective right hemicolectomy after a second episode, and typhlitis did not recur despite neutropenia associated with a subsequent course of chemotherapy. [doi.org]

• Leukopenia

  Compared with chemotherapy alone, SFI plus chemotherapy had lower 3/4 grade toxicity for leukopenia (risk ratio [RR] 0.34; 95% confidence intervals [95% CIs] 0.21-0.55), thrombocytopenia (RR 0.36; 95% CI 0.19-0.71), anemia (RR 0.39; 95% CI 0.16-0.99), [ncbi.nlm.nih.gov]

  They can help prevent leukopenia in people with a high risk. Nervous system effects. Some drugs cause nerve damage. [cancer.net]

  A low white blood cell count (neutropenia or leukopenia) increases the risk for infection. A low platelet count (thrombocytopenia) increases the risk for bruising and bleeding. [cancer.ca]

• Hyperuricemia

  The syndrome is characterized by hyperuricemia, hyperphosphatemia, hypocalcemia, hyperkalemia, and ARF ( 15, 16 ). [doi.org]

There’s time in between treatments to allow your body to recover. If you are receiving targeted therapy for early HER2-positive breast cancer, treatment could last up to a year. [mskcc.org]

Chemotherapy for Cancer Treatments Chemotherapy Basics What is Chemotherapy? Chemotherapy, or "chemical treatment," has been around since the days of the ancient Greeks. [my.clevelandclinic.org]

There are many chemotherapy drugs used for the treatment of mesothelioma cancer, though the standard first-line treatment is cisplatin or carboplatin with pemetrexed. [mesothelioma.com]

Hopefully, this information will help prepare you to talk with your treatment team and to feel more confident about your treatment plan. [foundationforwomenscancer.org]

Reduced drug sensitivity may cause the failure of chemotherapy and affect the prognosis of patients with cancer. [ncbi.nlm.nih.gov]

Laboratory and instrumental examinations performed did not suggest any specific etiology. After 15 days of medical support, the patient presented a complete cardiac function and clinical recovery. [ncbi.nlm.nih.gov]

Epidemiology Common in uncircumcised newborns or uncircumcised men with poor hygiene and accumulation of smegma May be due to poor hygiene, sexual transmission or associated with dermatologic disorders Etiology Due to propensity of pathogenic bacteria [pathologyoutlines.com]

Browse issues Year Issue Browse by volume Browse supplements Volume 72, Issue 8 August 2017 Cover image Cover image ISSN 0305-7453 EISSN 1460-2091 Issue navigation Reviews Original research Research letters Next > Reviews Editor's Choice Global epidemiology [academic.oup.com]

Epidemiology Common in uncircumcised newborns or uncircumcised men with poor hygiene and accumulation of smegma May be due to poor hygiene, sexual transmission or associated with dermatologic disorders Etiology Due to propensity of pathogenic bacteria [pathologyoutlines.com]

Gastroenterology and Hepatology (34) Surgery, Traumatology and Orthopaedics (32) Infectology (31) Anatomy (26) Histology, Embryology (24) Microbiology (23) Pharmacology (19) Emergency Medicine (17) Respiratory Medicine (17) Immunology, Allergology (16) Epidemiology [portal.mefanet.cz]

This is illustrated by molecular epidemiologic studies of environmental carcinogens such as polycyclic aromatic hydrocarbons and aromatic amines. [doi.org]

CONCLUSIONS: This rare event stresses our inability to correctly predict the risk of a patient developing cardiotoxicity and also highlights the need to improve the knowledge of underlying pathophysiological mechanisms; in fact, it suggests a possible [ncbi.nlm.nih.gov]

Internal Medicine (55) Medical Chemistry and Biochemistry (54) Pathology and Forensic Medicine (54) Physiology and Pathophysiology (49) Paediatrics, Neonatology (46) Gastroenterology and Hepatology (34) Surgery, Traumatology and Orthopaedics (32) Infectology [portal.mefanet.cz]

Read NW, Timms JM (1986) Defecation and the pathophysiology of constipation. Clin Gastroenterol 15:937–965 PubMed Google Scholar 56. [doi.org]

Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 65. Updated by: Michael M. [medlineplus.gov]

Abstract BSTRACT Introduction: The aim of this study was to investigate the potential role of melatonin in the prevention of chemotherapy-induced nephrotoxicity at the preclinical level. [ncbi.nlm.nih.gov]

The objective of this review was to establish whether preventive antibiotic therapy (prophylaxis) before the development of fever prevents illness and death in people with a low white blood cell count after chemotherapy and to assess whether certain types [doi.org]

If a preventive treatment is discovered, “you're not only preventing a condition that can cause months or even years of suffering, but it's the pain and the neuropathy that is limiting the dose of these drugs,” Bennett said. [jnci.oxfordjournals.org]