There is usually an accompanying high fever with painful skin tissue loss, and many signs including sore throat, abdominal pain, splenomegaly (enlarged spleen), conjunctival
[news-medical.net]
Systemic symptoms may include high fever, sore throat, diarrhoea, abdominal pain, central nervous system symptoms, lung disease, enlarged spleen, arthritis, sepsis, anaemia
[dermnetnz.org]