Secondary Amenorrhea: Causes & Reasons

Possible Causes for Secondary Amenorrhea

A young patient with secondary amenorrhea and primary infertility is described. [ncbi.nlm.nih.gov]

amenorrhea, secondary amenorrhea (diagnosis), Amenorrhoea secondary, amenorrhoea secondary, amenorrhea secondary, Secondary amenorrhoea (finding), Secondary Amenorrhea, Secondary [fpnotebook.com]

After a gynecological-endocrinological exploration including laparoscopy, the diagnosis indicates secondary hypergonadotropic, hypo-estrogenic normo-androgenic amenorrhea. [ncbi.nlm.nih.gov]

Asherman Syndrome

Asherman's syndrome secondary amenorrhea in a hormonally normal woman, caused by obliteration of the endometrial cavity by adhesions that form as a result of curettage, infection [medical-dictionary.thefreedictionary.com]

A 27-year-old Zulu woman, para 1, presented with secondary amenorrhea after an uncomplicated cesarean delivery. Hormone levels were in the normal ranges. [ncbi.nlm.nih.gov]

amenorrhea is typical. [checkorphan.org]

Virilization

We describe a 14-year-old patient with 1-year secondary amenorrhea, who had an ovarian mature teratoma as a cause of her clinical history. [ncbi.nlm.nih.gov]

A Chinese adolescent girl presented with secondary amenorrhea. During follow-up, she gradually developed Cushingoid features and virilization. [ncbi.nlm.nih.gov]

A 33-year-old woman presented to an endocrinology clinic with a 5-year history of secondary amenorrhea. 2 years before presentation, she had noticed progressively worsening [ncbi.nlm.nih.gov]

Premature Ovarian Failure

Three women at the age of 25, 30 and 32 years presented with 5, 6 and 10 years secondary amenorrhea, respectively. [ncbi.nlm.nih.gov]

It is characterized by absent menarche (primary amenorrhea) or premature depletion of ovarian follicles (secondary amenorrhea). [uniprot.org]

[…] of 40 years (secondary amenorrhea). [ncbi.nlm.nih.gov]

Autoimmune Ovarian Failure

METHOD OF STUDY: The medical history of three young women who presented with secondary amenorrhea following HPV vaccination was collected. [ncbi.nlm.nih.gov]

or premature depletion of ovarian follicles before the age of 40 years (secondary amenorrhea). [ojrd.biomedcentral.com]

Serum anti-müllerian hormone levels in women with secondary amenorrhea. Fertil Steril 85: 1547, 2006. [link.springer.com]

46,XX Ovotesticular Disorder of Sex Development

It is characterized by the presence of primary amenorrhea with or without normal secondary sexual characteristics. [advbiores.net]

However, affected individuals present during adolescence or young adulthood with either delayed or absent puberty resulting in primary or sometimes secondary amenorrhea. [orpha.net]

1], [2] Also, if a patient had no secondary sexual characteristics and no menarche, primary amenorrhea could be diagnosed even in 14 years of age. [advbiores.net]

Sheehan Syndrome

CLINICAL CHARACTERISTICS Signs and Symptoms • Secondary amenorrhea • Secondary hypothyroidism • Adrenal insufficiency (the degree of pituitary damage and resultant loss is [clinicalgate.com]

A 25-year-old woman presented with lactation failure, secondary amenorrhea, features of hypothyroidism and a hypocortisol state following severe postpartum hemorrhage after [ncbi.nlm.nih.gov]

After this episode she started having acyclic menses, occurring after prolonged periods of time, followed by secondary amenorrhea. [austinpublishinggroup.com]

Hyperprolactinemia

In women it is usually associated with galactorrhea and secondary amenorrhea; in men it may be a factor in gynecomastia, decreased libido, and impotence. [medical-dictionary.thefreedictionary.com]

Frequency United States This condition occurs in less than 1% of the general population and in 5-14% of patients presenting with secondary amenorrhea. [3] Approximately 75% [emedicine.com]

Methods: We retrospectively evaluated our outpatient admission records for PCOS, hirsutism, oligomenorrhea, or secondary amenorrhea. [endocrine-abstracts.org]

Ovarian Sertoli Cell Tumor

In many cases secondary amenorrhea is the only symptom of the disease. This leads to an intensive search for the source of the disorder. [ncbi.nlm.nih.gov]

The recommendation to include the measurement of androgen levels in the routine diagnosis of secondary amenorrhea must therefore be endorsed. [ncbi.nlm.nih.gov]

Forbes-Albright Syndrome

Moreover, we Distinguish primary amenorrhea, a when at the age of 18 years have not yet Appeared flows menstrual, and secondary amenorrhea, a when you have amenorrhea for [brainscape.com]

Secondary amenorrhea with galactorrhea. Enlargement of the sella turcica. No known specific anesthetic considerations for this syndrome. [accessanesthesiology.mhmedical.com]

[Prolactin-secreting hypophyseal adenomas as a cause of secondary amenorrhea and galactorrhea]. Bogdanova EA. Bogdanova EA. Akush Ginekol (Mosk). 1979 Oct;(10):5-7. [pubmed.ncbi.nlm.nih.gov]

Turner Syndrome

[…] congenital heart defects skeletal abnormalities webbed neck peripheral lymphedema More key diagnostic factors Other diagnostic factors dysmorphic features secondary amenorrhea [bestpractice.bmj.com]

Primary or secondary amenorrhea occurs with ovarian failure. [emedicine.medscape.com]

0000786 Recurrent otitis media Recurrent middle ear infection 0000403 Retrognathia Receding chin Receding lower jaw Weak chin Weak jaw [ more ] 0000278 Secondary amenorrhea [rarediseases.info.nih.gov]

Polycystic Ovary Syndrome

She was advised to visit the endocrinology department for secondary amenorrhea and endocrine survey. [ncbi.nlm.nih.gov]

Patient 4 had prepubertal overgrowth that evolved into pseudo-acromegaly, insulin resistance, secondary amenorrhea, and androgen excess at 15.6 years. [ncbi.nlm.nih.gov]

Symptoms of PCOS include changes in the menstrual cycle, such as: Not getting a period after you have had one or more normal ones during puberty ( secondary amenorrhea ) Irregular [nlm.nih.gov]

Menopause Ovarian Disorder

In secondary amenorrhea, menstruation starts but then stops. [froedtert.com]

Among younger women (aged 30 years or younger) with secondary amenorrhea, 13% also have been noted to have an abnormal karyotype ( 5 ). [acog.org]

Amenorrhea — absence or cessation of menstruation. In primary amenorrhea, menstruation never occurs at puberty. [froedtert.com]

Prolactinoma

In women of reproductive age, the symptoms are typically oligomenorrhea or secondary amenorrhea, galactorrhea, and sterility, followed by decreased libido, dry vaginal mucosa [ncbi.nlm.nih.gov]

amenorrhea. [symptoma.com]

Such alterations appear in adolescent females as delayed puberty (48% in our experience), primary amenorrhea (14–41%), secondary amenorrhea (29–45%) and oligomenorrhea (up [karger.com]

Panhypopituitarism

The patient who suffered from secondary amenorrhea was found a nonfunctioning pituitary macroadenoma, and the hormone test showed serum cortisol, FT3, FT4, thyrotropic hormone [ncbi.nlm.nih.gov]

The administration of purified growth hormone to a female with hypoadrenalism, hypothyroidism, diabetes mellitus and secondary amenorrhea, simulating panhypopituitarism. [amjmed.com]

Prolactin deficiency Women: lactation failure following delivery Men: asymptomatic FSH/LH deficiency Women: primary amenorrhea (delayed puberty), secondary amenorrhea, irregular [amboss.com]

Gonadoblastoma

A 28-year-old woman with well-developed female secondary sexual characteristics, secondary amenorrhea, short stature and a few somatic anomalies of streak gonad syndrome who [ncbi.nlm.nih.gov]

In these patients, there are failure to develop normal secondary sex characteristics, amenorrhea, or short stature at puberty and the ovaries are reduced to atrophic fibrous [jpatholtm.org]

Abstract 46,xy pure gonadal dysgenesis is a rare disorder, which is characterized by female phenotype, infantile female external genitalia, deficient secondary sexual development [ncbi.nlm.nih.gov]

Empty Sella Syndrome

The case of a 37-year-old woman with secondary amenorrhea and clear signs of hyperandrogenism is reported. [ncbi.nlm.nih.gov]

Endocrine Studies Clinical endocrine dysfunction is rare in adult patients with the empty sella syndrome; significant abnormalities are largely restricted to secondary amenorrhea [pituitaryadenomas.com]

HAIR-AN Syndrome

The patient presented here is a 21 year-old woman who has secondary amenorrhea, hirsutism, and hyperpigmented skin changes. [agris.fao.org]

A 20-year-old girl, having had a five-year-old secondary amenorrhea. [hindawi.com]

"A case of HAIR-AN syndrome presenting as secondary amenorrhea". Saudi Med J. 1996; 17: 520–2. 2. Barbieri RL, Ryan KJ. [annsaudimed.net]

Endometritis

In this article, we discuss a rare case of a 40-year-old Nigerian female presenting with abdominal pain, distension and secondary amenorrhea, and show that a high clinical [ncbi.nlm.nih.gov]

Pituitary Disorder

Clinical Practice Jul 22, 2010 Functional Hypothalamic Amenorrhea Gordon C.M. | N Engl J Med 2010; 363:365-371 A 16-year-old girl presents for evaluation of secondary amenorrhea [nejm.org]

Estrogen deficiency in approximately 50% of premenopausal women with secondary amenorrhea is attributable to acquired gonadotropin-releasing hormone (GnRH) dysregulation, [hindawi.com]

Hyperprolactinemia Hyperprolactinemia causes secondary hypogonadism and may have sex hormone-independent effects on bone metabolism [17, 18]. [hindawi.com]

Chronic Alcoholism

ENDOCRINE – Cirrhosis leading to gynecomastia and testicular atrophy, amenorrhea/infertility. Alcohol can also cause hypoglycemia in alcoholics. [errolozdalga.com]

ONCOLOGY – alcohol predisposes to multiple cancers, most notably Hepatocellular carcinoma (secondary to cirrhosis), also ENT and esophageal cancers (synergistic with smoking [errolozdalga.com]

Ectopic Pregnancy

She had secondary amenorrhea for nine weeks. Transvaginal ultrasonography revealed normal empty uterus and right interstitial ectopic pregnancy with viable embryo. [ncbi.nlm.nih.gov]

Hypothalamic Lesion

Case 2 A 21-year-old woman was referred for secondary amenorrhea. She had been treated for seven years with DDAVP for DI. [em-consulte.com]

Anorexia Nervosa

Anorexia nervosa Treatment of secondary amenorrhoea and infertility Secondary amenorrhea is a hallmark of anorexia nervosa. [jeatdisord.biomedcentral.com]

Endocrine symptoms in anorexia nervosa include hypothermia (feeling cold), delayed onset of menses or secondary amenorrhea, and osteopenia progressing to osteoporosis. 11, [aafp.org]

Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake. [jeatdisord.biomedcentral.com]

Tubal Pregnancy

Secondary amenorrhea varies, as nearly half of women with tubal pregnancies have some spotting at the time of their expected menses and thus do not realize they are pregnant [symptoma.com]

Adrenogenital Syndrome

However, because they do not have female internal reproductive organs, these individuals have amenorrhea and do not develop female secondary sex characteristics. [ncbi.nlm.nih.gov]

Women with complete 17a-hydroxylase/17,20-lyase deficiency do not develop secondary sex characteristics, such as breasts and pubic hair, and do not menstruate (amenorrhea) [ncbi.nlm.nih.gov]

Women with partial 17a-hydroxylase/17,20-lyase deficiency may develop some secondary sex characteristics; menstruation is typically irregular or absent. [ncbi.nlm.nih.gov]

Pituitary Apoplexy

( delayed puberty ), secondary amenorrhea, irregular menstrual cycles, infertility Males: delayed puberty, loss of libido, infertility, testicular atrophy, loss of facial [amboss.com]

[…] include weight gain, weakness, and depression Prolactin deficiency Females: lactation failure following delivery Males: asymptomatic FSH / LH deficiency Females: primary amenorrhea [amboss.com]

Pituitary Cushing Syndrome

“Minnie G.,” as she became historically known, presented with a “… syndrome of painful obesity, hypertrichosis, and amenorrhea with overdevelopment of secondary sexual characteristics [doi.org]

hypertrichosis (abnormal hair growth), underdevelopment of secondary sexual characteristics, hydrocephalus and cerebral tension.[3] This combination of symptoms was not [en.wikipedia.org]

Harvey Cushing in 1912, after he was presented with a unique case of the disease in 1910[23][24] a 23-year-old woman called Minnie G. whose symptoms included painful obesity, amenorrhea [en.wikipedia.org]

Ovarian Cyst

A 19-year-old unmarried woman with regular menstrual cycles presented with symptoms of vague abdominal pain of 1 month duration. General condition fair. Per abdomen-a firm, non-tender mass corresponding to 26 weeks of gestation with smooth surface, upper and lateral borders well defined, lower border not palpable[…] [ncbi.nlm.nih.gov]

Female Pelvic Inflammatory Disease

Abstract Pelvic inflammatory disease (PID) is a clinical syndrome of the female reproductive tract characterized by inflammation of the endometrium, fallopian tubes, or peritoneum (1). PID occurs when microorganisms ascend from the vagina or cervix to the fallopian tubes and other upper genital tract structures (1).[…] [ncbi.nlm.nih.gov]