Muscle Spasticity: Causes & Reasons

Possible Causes for Muscle Spasticity

Oral antispastic agents are usually indicated in patients with diffuse or regional muscle spasticity rather than localized muscle spasticity. [cambridge.org]

Involvement of UMN results in stiffness of muscles (spasticity) and slowed movements. [mndnsw.asn.au]

This leads to muscle weakness and atrophy on both sides of the body. Muscles become spastic, spasm and display uncontrollable twitches. [theconversation.com]

Cerebral Palsy

RESULTS: Significant changes were observed in the children's gross motor function and muscle spasticity, as evidenced by the GMFM-88 total score, scores for each of its domains [ncbi.nlm.nih.gov]

Reducing muscle spasticity may be an important goal of treatment. [chasa.org]

Spastic cerebral palsy This is by far the most common type of cerebral palsy accounting for around 70% of cases. It presents with stiff or spastic muscles. [symptoma.com]

Spastic Paraplegia

Drug Treatment – Muscle Spasticity The most commonly used drugs to help ease spasticity include oral and intrathecal Baclofen and Tizanidine, Diazepam and Clonazepam, and [sp-foundation.org]

It is accompanied by irritability and spastic contractions of the leg muscles. spastic paraplegia Paralysis of both lower limbs with muscle spasm. [medical-dictionary.thefreedictionary.com]

Spastic paraplegia type 8 is a pure hereditary spastic paraplegia.Like all hereditary spastic paraplegias, spastic paraplegia type 8 involves spasticity of the leg muscles [icdlist.com]

Cerebral Palsy with Spastic Diplegia

Pain – persistent overactivity in spastic muscles can cause pain in the muscle. [cerebralpalsy.org.au]

Botulinum toxin medication helps to reduce the spasticity from muscle. [trishlafoundation.com]

Spastic is the most common form of cerebral palsy which affects 70 to 80 percent of patients. Spastic cerebral palsy symptoms include increased tension in a muscle. [cerebralpalsylawdoctor.com]

Paraplegia

Firstly, chronic spasticity might be a risk factor for histopathological muscle alterations. [ncbi.nlm.nih.gov]

Their primary symptoms are progressive spasticity and weakness of the leg and hip muscles. [sp-foundation.org]

Treatment is mainly supportive, with skeletal muscle relaxants, botulinum toxin, and physiotherapy for muscle spasticity. [amboss.com]

Hereditary Spastic Paraplegia

Firstly, chronic spasticity might be a risk factor for histopathological muscle alterations. [ncbi.nlm.nih.gov]

Their primary symptoms are progressive spasticity and weakness of the leg and hip muscles. [sp-foundationorg.presencehost.net]

This case raises questions about the pathophysiology of muscle ruptures in highly functional patients with hereditary spastic paraplegia (HSP) who have only minor spasticity [ncbi.nlm.nih.gov]

Amyotrophic Lateral Sclerosis

This is a progressive and fatal disease, with initial complaints about muscle spasticity followed by progressively worsening muscle weakness. [fusfoundation.org]

spastic muscles Reciprocal actions are attempted. [en.wikipedia.org]

Also known as Lou Gehrig’s disease in the US and motor neuron disease in the UK, ALS is characterized both by muscle spasticity and a progressive weakening of the muscles. [youtube.com]

Quadriplegia

We evaluated the adverse events, walking time and distance, and the difference in muscle spasticity before and after HAL-training using a modified Ashworth scale (mAs). [ncbi.nlm.nih.gov]

[…] injected into the spine to reduce muscle spasticity. [oaklandortho.com]

spasticity ) 神経症状 ( neurologic manifestation ) 脊髄損傷 ( spinal cord injury ) 診断 ( diagnosis ) 神経系疾患 ( nervous system disease ) 脳性麻痺 ( cerebral palsy ) 構音障害 ( dysarthria ) 脊髄疾患 [lsd-project.jp]

Lissencephaly

Children who are born with lissencephaly suffer from severe motor impairment, seizures, muscle spasticity, muscle hypotonia, facial abnormalities, difficulty swallowing, abnormalities [disabilitybenefitscenter.org]

They usually present with seizures, muscle spasticity, low muscle tone and a number of other neurological symptoms. [disability-benefits-help.org]

Amyotrophic Lateral Sclerosis Type 9

DO ID DOID:332 Description A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing [yeastgenome.org]

spasticity and stiffness, and modest muscle atrophy.1 PLS cannot be diagnosed as ALS until there is evidence of LMN dysfunction of at least 1 limb or region and it progresses [ajmc.com]

Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. [ncbi.nlm.nih.gov]

Fucosidosis

The infantile form (type I) features psychomotor deterioration, MUSCLE SPASTICITY, coarse facial features, growth retardation, skeletal abnormalities, visceromegaly, SEIZURES [connects.catalyst.harvard.edu]

[…] contractions (spasticity) distinctive facial features (coarse facial features) recurrent respiratory infections clusters of small, dark red spots on the skin (angiokeratomas [childrenshospital.org]

[…] intellectual disability delay in motor skills development impaired or slow growth (failure to thrive) abnormal skeletal development (dysostosis multiplex) seizures abnormal muscle [childrenshospital.org]

Pelizaeus-Merzbacher Disease

PMD is an extremely rare mother-to-son genetic condition characterized by nystagmus (involuntary rolling of the eyes) and hypotonia (low muscle tone) and eventually spasticity [globalgenes.org]

The disease is clinically characterized by nystagmus (rhythmical oscillation of the eyes), impaired motor development, tremor, progressive spasticity (increased muscle tone [medicinenet.com]

[…] contractures Spasticity Mental deterioration Convulsions Skeletal deformation 4 Causes Mutations in the PLP1 gene cause Pelizaeus- Merzbacher disease. [slideplayer.com]

Spinal Cord Transection

spasticity (increased muscle tone) management Medications and alternative methods of managing pain and spasticity Psychological counseling Identifying problems and solutions [urmc.rochester.edu]

Muscle hypertonia with spastic paresis Increased proprioceptive reflex: hyperreflexia Inexhaustible clonus : e.g., ankle clonus Anal reflex remains absent Pathological reflexes [amboss.com]

Spasticity can reduce venous pooling and stabilize the thoracic and abdominal muscles used in respiration. [americannursetoday.com]

Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome

If left untreated, this can result in developmental delay, learning disabilities, or stiffness caused by abnormal tensing of muscles (spasticity). [eugenelabs.com]

(spasticity). [medlineplus.gov]

Complications of ornithine translocase deficiency may include developmental delay, learning disabilities, and stiffness caused by abnormal tensing of the muscles (spasticity [ghr.nlm.nih.gov]

Cervical Spinal Cord Injury

spasticity (increased muscle tone) management Medicines and alternative methods of managing pain and spasticity Psychological counseling Identifying problems and solutions [hopkinsmedicine.org]

An injection of Botulinum toxin (Botox) into spastic muscles is a treatment to reduce spasticity. This can be used to prevent muscle shorting and early contractures. [en.wikipedia.org]

Some people with spinal cord injuries experience one of two types of muscle tone problems: uncontrolled tightening or motion in the muscles (spasticity) or soft and limp muscles [mayoclinic.org]

Stiff-Person Syndrome

Oral medications were unable to control his muscle spasticity, preventing him from working. [ncbi.nlm.nih.gov]

Muscle spasticity can fluctuate from hour to hour, abate with sleep, and get worse with emotional distress. [mdedge.com]

Stiff-person syndrome is a progressive disease of muscle rigidity and spasticity due to a deficiency in the production of γ-aminobutyric acid. [ncbi.nlm.nih.gov]

Multiple Sclerosis

[…] contractures neurological examination muscle spasticity increased deep tendon reflexes muscle weakness Babinski positive special tests fundoscopy MLF syndrome (Internuclear [orthobullets.com]

A significant amount of evidence suggests THC and CBD -based medications can be used for treating muscle spasticity associated with multiple sclerosis, but most studies have [leafly.com]

The symptoms of MS are highly varied but frequently include pain, muscle spasticity, fatigue, inflammation, and depression. [frontiersin.org]

Spinal Cord Injury

spasticity (increased muscle tone) management Medicines and alternative methods of managing pain and spasticity Psychological counseling Identifying problems and solutions [hopkinsmedicine.org]

Damage to the spinal cord usually results in impairments or loss of: Movement/Muscle Control Inability to move muscles Muscles may have spastic contractions or may atrophy [themiamiproject.org]

Juvenile Parkinson Disease of Hunt

This feature helps to distinguish rigidity from muscle spasticity. [ncbi.nlm.nih.gov]

In central paralysis the tone of the muscles is increased, causing spasticity. [medical-dictionary.thefreedictionary.com]

Nerve regeneration or regrowth is one way in which strength can return to a paralyzed muscle. Paralysis almost always causes a change in muscle tone. [medical-dictionary.thefreedictionary.com]

Arnold-Chiari Malformation

spasticity, and episodic urinary retention. [dynamicchiropractic.com]

[…] strength in the hands and arms (as a result of a syrinx) Drop attacks – collapsing to the ground due to muscle weakness Spasticity Dizziness Balance problems Double or blurred [aans.org]

Arnold-Chiari malformation), facial weakness, dysphonia, apnea, tongue atrophy, diplopia, and signs of spinal cord compression such as the Babinski's sign, hemiparesis, muscle [dynamicchiropractic.com]

Hydrocephalus

spasticity (spasm) Slow growth (child 0 to 5 years) Slow or restricted movement Vomiting The health care provider will examine the baby. [nlm.nih.gov]

spasticity (spasm) Slow growth (child 0-5 years) Slow or restricted movement Vomiting When a health care provider taps fingertips on the skull, there may be abnormal sounds [web.archive.org]

Difficulty feeding Excessive sleepiness Headache Irritability, poor temper control Loss of bladder control (urinary incontinence) Loss of coordination and trouble walking Muscle [nlm.nih.gov]

Tetanus Neonatorum

Dantrolene Dantrolene is sometimes prescribed in cases of chronic (long-term) muscle spasticity (where your muscles are overly tight or rigid). [hse.ie]

In localized tetanus, there is spasticity of muscles near the entry wound but no trismus; spasticity may persist for weeks. [msdmanuals.com]

A stammering with difficulties in pronouncing "guttural" sounds due to spasm of the laryngeal muscles. local tetanus Tetanus marked by spasticity of a group of muscles near [wordinfo.info]

Spinal Cord Compression

Muscle spasticity can cause spasms in the legs or make them more difficult to control. [livestrong.com]

An increase of muscle tone during these passive movements is referred to as "spasticity." [neuroanatomy.wisc.edu]

Stroke

Spasticity and muscle weakness are common severe neurologic sequelae after stroke. [ncbi.nlm.nih.gov]

It can allow for excellent spasticity control, especially in the elbow and thigh muscles. [upmc.com]

Muscles that are not used usually become permanently spastic and stiff, and painful muscle spasms may occur. [msdmanuals.com]

Niemann-Pick Disease Type C

[…] to touch, spasticity (stiff muscles and awkward movement), and slurred speech. [ninds.nih.gov]

Neurological symptoms may include ataxia (lack of muscle control during voluntary movements such as walking), loss of muscle tone, brain degeneration, increased sensitivity [ninds.nih.gov]

Parkinson Disease

spastic muscles Reciprocal actions are attempted. [en.wikipedia.org]

[…] paraplegia 0001258 Spasticity Involuntary muscle stiffness, contraction, or spasm 0001257 Supranuclear gaze palsy 0000605 Torticollis Wry neck 0000473 Tremor Tremors 0001337 [rarediseases.info.nih.gov]

[…] for preventing muscle contractures on patients with spasticity. [en.wikipedia.org]

Cervical Myelopathy

[…] paresis, and spasticity; nerve root compression commonly causes early radicular pain, sometimes followed by weakness, hyporeflexia, and muscle atrophy. [merckmanuals.com]

muscle weakness, and/or numbness (sensory deficits). [uscspine.com]

Loss of motor strength, sensory changes, wasting of the intrinsic muscles of the hand, and spasticity may dramatically decrease upper extremity function and the condition [boneandspine.com]

Gaucher Disease Type 2

[…] paralysis 0000602 Spasticity Involuntary muscle stiffness, contraction, or spasm 0001257 Splenomegaly Increased spleen size 0001744 Strabismus Cross-eyed Squint Squint eyes [rarediseases.info.nih.gov]

[…] stiffness in the leg muscles, and epilepsy. [socialstyrelsen.se]

[…] swallowing Swallowing difficulties Swallowing difficulty [ more ] 0002015 Dystonia 0001332 Encephalopathy 0001298 Hepatomegaly Enlarged liver 0002240 Ophthalmoplegia Eye muscle [rarediseases.info.nih.gov]

Gaucher Disease

[…] manifestations of GD, such as scoliosis caused by muscle spasticity and respiratory function. [ncbi.nlm.nih.gov]

Affected infants may lose previously acquired motor skills and exhibit low muscle tone (hypotonia), involuntary muscle spasms (spasticity) that result in slow, stiff movements [rarediseases.org]

Intrathecal baclofen therapy (IBT) is indicated for spastic neurological diseases, such as cerebral palsy, and studies have shown its therapeutic benefit in improving several [ncbi.nlm.nih.gov]

Cervical Spondylosis

The main clinical features are localized wasting and weakness of the extrinsic and intrinsic hand muscles, but not accompanied by either sensory loss or spastic quadriparesis [ncbi.nlm.nih.gov]

There is often proximal weakness of the lower extremities (mild to moderate iliopsoas muscle weakness occurs in about 50%) and a spasticity of the lower extremity. [termedia.pl]

[…] dysfunction) generalized weakness throughout muscle groups, especially in the extremities poor or pathologic tandem gait atrophy of the hand’s thenar prominence (the fleshy [americannursetoday.com]