MUSCULOSKELETAL SYSTEM Musculoskeletal involvement is present in 95% of patients with SLE and manifests as arthralgias, myalgias, or nonerosive inflammatory arthritis. 10
[aafp.org]
[…] keratoconjunctivitis sicca, retinopathy), gastrointestinal (oral ulceration, abdominal pain), cardiac (atherosclerosis, chest pain), pulmonary (serositis, pleurisy), musculoskeletal (arthralgia
[orpha.net]
Antimalarials, e.g., hydroxychloroquine, can use to treat arthralgia and skin disease.
[ncbi.nlm.nih.gov]