Arthralgia: Causes & Reasons - Symptoma Ireland

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Possible Causes for Arthralgia

Polyarthritis

Although bisphosphonates are safety drugs, they have numerous side-effects such as arthralgia, elevated erythrocyte sedimentation rate and C-reactive protein, gastrointestinal [ncbi.nlm.nih.gov]

Hydroxychloroquine treatment was introduced 5 months after the onset of polyarthritis because of persisting inflammatory arthralgia. [ncbi.nlm.nih.gov]

The patient reported no arthralgias and continued compliance with prasugrel during follow-up telephone calls by the clinical pharmacist at two and six weeks. [ncbi.nlm.nih.gov]

Erythema Nodosum

In this case report, we suggest arthralgia, EN, and Achilles tendinitis could coexist with AGPB. [ncbi.nlm.nih.gov]

Fifty percent of patients with erythema nodosum also have generalized arthralgia which usually precedes the rash. [symptoma.com]

Erythema nodosum leprosum (ENL) is characterized by tender erythematous nodules, accompanied by fever, malaise, arthralgia, and systemic complications. [ncbi.nlm.nih.gov]

Viral Arthritis

Low Arthritis, arthralgia with acute infection. [racgp.org.au]

Synovitis is minimal and in general arthralgia is more common than frank arthritis. [rheumatologyadvisor.com]

BACKGROUND: Arthralgia is a common presentation to general practice, and many cases will not require any specific treatment. [ncbi.nlm.nih.gov]

Syphilitic Arthritis

Syphilis arthralgia (arthralgia syphilitica). Can meet soon after syphilis infection in the second and third period. [lecheniebolezni.com]

Intermittent arthralgias and myal-gias—but not arthritis—occur within days or weeks of inoculation of the spirochete by the Ixodes tick. [what-when-how.com]

Joint Lesions in Acquired Syphilis Arthralgia Arthralgia forms part of the clinical picture in the secondary stage. It may even appear before the early rashes. [boneandspine.com]

Leukocytoclastic Vasculitis

The patient sought emergency treatment presenting with headache, arthralgia, cutaneous rash, and weight loss (4 kg) in the last 20 days. [ncbi.nlm.nih.gov]

Arthralgia occurred in 20 per cent of the patients. [ncbi.nlm.nih.gov]

Many patients develop skin lesions, particularly on the legs, accompanied by arthralgia and fever. The disorder is seen in rheumatoid arthritis and other diseases. [medical-dictionary.thefreedictionary.com]

Henoch-Schönlein Purpura

She initially presented with arthralgia and murmur. Echocardiography showed mild to moderate mitral regurgitation. [ncbi.nlm.nih.gov]

Arthritis/arthralgia may be a risk factor according to the criteria of the American College of Rheumatology (1.41, 1.01-1.96). [ncbi.nlm.nih.gov]

Cutaneous purpura is universal in the disease, with arthralgias in about two-thirds of the cases, but arthritis is rare. [the-rheumatologist.org]

Cryopyrin-Associated Periodic Syndrome

Arthralgia, particularly at the knee joint, accompanied the presentation of urticaria (Fig. 1). [ncbi.nlm.nih.gov]

[…] syndrome caused by mutations of the CIAS1 gene (currently named NLRP3), and is characterized by periodic attacks of an urticaria-like rash, fever, head-ache, conjunctivitis and arthralgia [ncbi.nlm.nih.gov]

FCAS is also characterized by intermittent arthralgia after cold exposure and MWS by acute episodes of arthralgia or arthritis, progressive bilateral sensorineural hearing [onlinelibrary.wiley.com]

Schnitzler Syndrome

The patient had also suffered from fever and right hip and left knee arthralgia. [ncbi.nlm.nih.gov]

Schnitzler syndrome is an autoinflammatory disease characterized by chronic, nonpruritic urticaria in association with recurrent fever, bone pain, arthralgia or arthritis, [emedicine.com]

[…] syndrome with cold-induced urticaria Abstract Background: Schnitzler syndrome encompasses monoclonal gammopathy, urticaria, inflammation, recurrent fever, bone pain and arthralgia [doi.org]

Lupus Erythematosus

MUSCULOSKELETAL SYSTEM Musculoskeletal involvement is present in 95% of patients with SLE and manifests as arthralgias, myalgias, or nonerosive inflammatory arthritis. 10 [aafp.org]

[…] keratoconjunctivitis sicca, retinopathy), gastrointestinal (oral ulceration, abdominal pain), cardiac (atherosclerosis, chest pain), pulmonary (serositis, pleurisy), musculoskeletal (arthralgia [orpha.net]

Antimalarials, e.g., hydroxychloroquine, can use to treat arthralgia and skin disease. [ncbi.nlm.nih.gov]

Acute Sarcoidosis

Systemic symptoms include fatigue, night sweats, weight loss, fever, arthralgia and myalgia. [ncbi.nlm.nih.gov]

Acute sarcoidosis has an abrupt onset with constitutional symptoms (e.g., fever, malaise) as well as cough, dyspnea, anterior uveitis, erythema nodosum, and arthralgia, and [amboss.com]

Familial Cold Autoinflammatory Syndrome Type 1

Abstract This is a case of a 26‐year‐old Caucasian woman with a lifelong history of an episodic urticaria associated with arthralgia, precipitated by exposure to cold. [onlinelibrary.wiley.com]

MWS is characterized by progressive sensorineural deafness as well as recurrent episodes of skin rash, fever and arthralgia (1). [medicaljournals.se]

Systemic symptoms included burning, chills, and arthralgias rather than the anaphylactic symptoms associated with acquired urticarias. [ncbi.nlm.nih.gov]

Microscopic Polyangiitis

We hereby present a 14-year-old girl with arthralgia, seizure, leukocytoclastic vasculitis, interstitial lung disease secondary to recurrent pulmonary hemorrhage, pauci-immune [ncbi.nlm.nih.gov]

Abstract A 68-year-old man, who had worked for processing quartz-containing stones for more than 50 years, complained of low-grade fever and arthralgia. [ncbi.nlm.nih.gov]

We report a case of a 76-year-old woman, presenting with a persistent dry cough, subfebrility, arthralgia and myalgia, weight loss and a breast lesion. [ncbi.nlm.nih.gov]

Adult-Onset Still Disease

Abstract Adult onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology characterized by spiking fever, evanescent skin rash, arthralgia or arthritis [e-ijd.org]

Severe malaise, myalgia, arthralgia, and leukocytosis were present in every patient. [ncbi.nlm.nih.gov]

Arthralgia is usually correlated with fever spikes. [orpha.net]

Systemic Juvenile Idiopathic Arthritis

Among the 13 patients with “suspected” sJIA, 6 patients had neither arthralgia nor arthritis and 7 patients had arthralgia without ever having had arthritis. [ped-rheum.biomedcentral.com]

The disease is characterized by the following features : hectic fever > 39° C, arthralgia or arthritis, rash, neutrophilia and systemic inflammation. [ncbi.nlm.nih.gov]

Clinically, the most classic manifestations of AOSD are fever, rash, sore throat, and arthralgia with fever and arthralgia being the most common among them [13]. [hindawi.com]

Hemochromatosis

Symptoms greatly vary among patients and include fatigue, abdominal pain, arthralgias, impotence, decreased libido, diabetes, and heart failure. [ncbi.nlm.nih.gov]

The prevalences of fatigue, arthralgia and abnormal liver test results were higher in our group (85.5 vs 36.1%; 78.3 vs 24.4% and 46.6 vs 16.8%). [nature.com]

Symptoms include fatigue,hyperpigmentation, diabetes mellitus ("bronze diabetes"), and arthralgia. [amboss.com]

Sweet Syndrome

It presents clinically with polymorphic skin lesions, fever, arthralgia, and peripheral leukocytosis. In general, it is associated with infections, malignancy and drugs. [ncbi.nlm.nih.gov]

Her course of disease was complicated by arthralgias, episcleritis, headaches, and erythema nodosum-like subcutaneous involvement. [ncbi.nlm.nih.gov]

Conclusions Patients with older age, anaemia or thrombocytopenia, and without arthralgia are more likely to have malignancy‐associated SS. [onlinelibrary.wiley.com]

Muckle-Wells Syndrome

Abstract The term Muckle-Wells syndrome (MWS) describes an autosomal dominant disorder characterised by various combinations of urticaria, sensorineural deafness, amyloidosis, arthralgia [ncbi.nlm.nih.gov]

Myalgia, arthralgias and distal edema are very common. With age, patients develop eythematous band over the hands as well as digital clubbing. [orpha.net]

[…] in MWS, but deafness is a feature of all reported pedigrees, we conclude that members of this family have a previously unreported inherited predisposition to urticaria, arthralgia [ncbi.nlm.nih.gov]

Granulomatosis with Polyangiitis

We report this case that presented with a productive cough, followed by arthralgia, DAH, and GIH. [ncbi.nlm.nih.gov]

Following treatment, the patient was asymptomatic for 6 weeks until he developed acute renal failure, generalised arthralgia, acute hypertensive anterior uveitis, and dacryoadenitis [ncbi.nlm.nih.gov]

General signs (fever, arthralgia, myalgia, weight loss) are common. [orpha.net]

CINCA Syndrome

In terms of joint involvement, recurrent flares that may be accompanied with overgrowth of the patella are most frequently reported, together with arthralgia that can be severe [symptoma.com]

MWS is characterized by progressive sensorineural deafness as well as recurrent episodes of skin rash, fever and arthralgia (1). [medicaljournals.se]

Familial Cold Autoinflammatory Syndrome (FCAS) This syndrome is characterized by: - Cold-induced attacks of fever - Urticaria-like rash (after cold exposure) - Arthralgia [immunodeficiencysearch.com]

Cryoimmunoglobulinemic Syndrome

Cryoglobulinemic vasculitis is characterized by the classical triad of purpura, weakness and arthralgia, frequent multiple organ involvement, and with infrequent late lymphatic [davidsyounger.com]

Clinical diagnoses included the purpura-weakness-arthralgias syndrome, posthepatitis cirrhosis, congestive heart failure and mitral stenosis. [karger.com]

 Recurrent apthous ulcer CD4+ cell ... disorder HIV-related vasculitis Clinical features:  palpable purpura  digital necrotic ulcers  swelling ... of hands & feet  arthralgia [docpile.net]

Hypocomplementemic Vasculitis

The arthralgias were intermittent and migratory, affecting the hands, knees, and ankles, and resolved spontaneously after 2 to 3 days. [jmedicalcasereports.biomedcentral.com]

Patients with this condition are likely to have systemic involvement, including angioedema, arthralgias, pulmonary disease, abdominal or chest pain, fever, renal disease, [diseaseinfosearch.org]

AHA-syndrome was ruled out based on the absence of arthritis/ arthralgia, Cogan’s syndrome due to the absence of keratitis (despite hearing loss). [omicsonline.org]

Rheumatic Fever

High ASO titers, arthralgia, and combination of high ASO titers with arthralgia are the main presenting symptoms in the group with a different diagnosis. [ncbi.nlm.nih.gov]

RESULTS: 'Atypical' pattern was present in 63% (39/62) of patients with articular manifestations, of which arthralgia was a common manifestation (57%). [ncbi.nlm.nih.gov]

The minor criteria include- arthralgia, fever, heart block, leucocytosis, raised ESR or CRP and history of rheumatic fever. [lifehugger.com]

Connective Tissue Disease

Early symptoms are non-specific, including easy fatigability, myalgia, arthralgia and Raynaud's phenomenon. [ncbi.nlm.nih.gov]

The most frequent onset symptoms of UCTD include arthralgias, arthritis, Raynaud's phenomenon, mucocutaneous involvement, and sicca symptoms. [ncbi.nlm.nih.gov]

The most characteristic symptoms of UCTD present in the form of arthralgias, arthritis and Raynaud's phenomenon. [go.gale.com]

Eosinophilia Myalgia Syndrome

On October 1989, eosinophilia and incapacitating myalgia, together with arthralgia, dyspnea, cough and edema of the extremities, were shown to be associated with L-tryptophan [ncbi.nlm.nih.gov]

The late-stage manifestations of EMS and TOS are muscle cramping, arthralgia, severe fatigue, and cognitive impairment. [ncbi.nlm.nih.gov]

Eight patients who became ill while taking tryptophan had myalgia, fatigue, rash, fever, edema, alopecia, arthralgias, diminished joint motion, skin tightening, muscle cramping [ncbi.nlm.nih.gov]

Mixed Connective Tissue Disease

Raynaud's phenomenon was the most common initial symptoms (50%), followed by arthralgia (30%) and swollen hands (16%). [ncbi.nlm.nih.gov]

A 35-year-old female of Asian origin was admitted to our hospital due to complaints of Raynaud's phenomenon, myalgia, arthralgia and fatigue. [ncbi.nlm.nih.gov]

Before diagnosis, 50% had Raynaud’s phenomenon; 30% had arthralgia; and 16% had swollen hands. [healio.com]

Hyper-IgD Syndrome

The febrile period is accompanied by lymphadenopathy, arthralgia, abdominal pain, diarrhea, aphthous ulcers, and varying degree of skin involvement. [ncbi.nlm.nih.gov]

Hyper-IgD syndrome is a periodic fever syndrome that presents with recurrent episodes of high fever accompanied by lymphadenopathy, abdominal distress, arthralgias or arthritis [ncbi.nlm.nih.gov]

We performed biochemical and molecular genetic analyses on 2 girls with periodic episodes of fever, skin rash, abdominal pain, and arthralgia, of whom 1 had elevated levels [ncbi.nlm.nih.gov]

Tumor Necrosis Factor Receptor 1-associated Periodic Syndrome

Most patients developed rash (erythema) (84.6 %) and arthralgia (73.3 %), and half suffered frommyalgia (54.5 %) and abdominal pain (50.0 %). [kyushu-u.pure.elsevier.com]

Abdominal pain and arthralgias are frequent symptoms. Secondary amyloidosis with renal and hepatic manifestations may eventually develop. [orpha.net]

Most patients developed rash (erythema) (84.6 {\%}) and arthralgia (73.3 {\%}), and half suffered frommyalgia (54.5 {\%}) and abdominal pain (50.0 {\%}). [kyushu-u.pure.elsevier.com]

Polyarteritis Nodosa

It is limited to the skin and has a recurrent and chronic course, possibly associated with fever, arthralgia, myalgia and neuropathy, but without visceral involvement. [ncbi.nlm.nih.gov]

Cutaneous polyarteritis nodosa (CPAN) is characterized by a necrotizing vasculitis of small and medium-sized arteries in the skin, which can be associated with fever, arthralgia [ncbi.nlm.nih.gov]

[…] report an F-FDG linear uptake of the right popliteal artery in a 25-year-old man who underwent a PET/CT scan for unexplained chronic asthenia associated with fever symptoms, arthralgia [ncbi.nlm.nih.gov]

Mevalonate Kinase Deficiency

The febrile period is accompanied by lymphadenopathy, arthralgia, abdominal pain, diarrhea, aphthous ulcers, and varying degree of skin involvement. [ncbi.nlm.nih.gov]

MKD is characterized by recurrent febrile attacks that are frequently accompanied by lymphadenopathy, gastrointestinal symptoms, arthralgia, myalgia, skin rash, and aphthous [ncbi.nlm.nih.gov]

Fever lasts 2-7 days and can be accompanied by malaise, headache, diarrhea, abdominal pain, vomiting, skin rashes, arthralgia, arthritis, tender lymphadenopathy, hepatosplenomegaly [ncbi.nlm.nih.gov]

Relapsing Polychondritis

However, arthralgia recurred as the dose of methylprednisolone was tapered to 30 mg daily. [rheumatology.oxfordjournals.org]

[…] vertigo, tinnitus (ringing in the ears) Ataxia of vestibular origin (loss of balance) Hearing impairment—46 percent of patients in later stages suffer from hearing problems Arthralgia [belmarrahealth.com]

Arthralgia (this may affect any synovial joint. However, metacarpophalangeal, proximal interphalangeal and knee joints are the most commonly affected). [patient.info]